Paper, 'On the disappearance of the leucocytes from the blood, after injection of peptone' by David Bruce

Description

Bruce writes: 'As is well known, the injection of a solution of peptone into the circulation of certain animals is followed immediately by a very considerable diminution in the number of white blood corpuscles in the circulating blood. Some investigators who have written on this subject ascribe this diminution to the destruction and breaking down of the leucocytes in the blood plasma. As this theory appeared to me to rest on the very slenderest evidence, and as it seemed to me much more natural to believe that a temporary withdrawal of the leucocytes into the internal organs took place, I was led to attempt the enumeration of the white blood corpuscles in sections of the various organs before and after the injection of peptone.'

Annotations in pencil and ink. Includes two plates of figures showing sections of the lung of a rabbit under the microscope.

Subject: Physiology / Haematology

Received 21 February 1894 / 2 March 1894. Read 15 March 1894. Communicated by Victor Horsley.

A version of this paper was published in volume 55 of the Proceedings of the Royal Society as 'On the disappearance of the leucocytes from the blood, after injection of peptone'.

Reference number

PP/23/20

Earliest possible date

1894

Physical description

Ink and graphite pencil on paper

Page extent

12 pages

Format

Manuscript
Drawing