Paper, 'On the presence of urea in the blood of birds, and its bearing upon the formation of uric acid in the animal body' by Alfred Baring Garrod

Description

Garrod writes: 'Some experiments upon which I have recently been engaged have yielded results which appear to be inconsistent with any explanation yet advanced of the mode of formation of uric acid in the animal body, and to necessitate a new theory of its formation. These results I propose to discuss in the present paper, but before doing so it will be well to refer briefly to the different views upon this subject which have been from time to time advanced. Until the year 1847 it was commonly supposed that uric acid was formed in the kidneys themselves, none having ever been detected in the blood, but in that year I succeeded in demonstrating the presence of uric acid in the blood of gouty subjects, which led to the conclusion that uric acid was formed in certain other organs and tissues of the body, and was merely eliminated by the kidneys.'

Annotations in pencil and ink.

Subject: Biology / Physiology

Received 2 May 1893. Read 18 May 1893.

A version of this paper was published in volume 53 of the Proceedings of the Royal Society as 'On the presence of urea in the blood of birds, and its bearing upon the formation of uric acid in the animal body'.

Reference number

PP/21/14

Earliest possible date

1893

Physical description

Ink and graphite pencil on paper

Page extent

14 pages

Format

Typescript