Paper, 'On the causation of diphtheritic paralysis' by Sidney Harris Cox Martin

Description

Martin writes: 'The paralysis following diphtheria in man is so closely associated with the acute disease that it is more correctly considered as a symptom and not a sequela. Its mode of production in man has not been demonstrated. A chemical examination of the blood and spleen of eight patients who had died of diphtheria revealed the presence of two classes of substances not normally present in the tissues of the body, viz. (1) of two albumoses or digested proteids, proto- and deutero-albumose, giving the same chemical reactions as the albumoses of peptic digestion, and (2) of an organic acid, which is soluble in absolute alcohol and in water, to a less extent soluble in amyl alcohol, and insoluble in ether, chloroform, or benzene.'

Annotations in pencil and ink.

Subject: Physiology / Pathology

Received 2 March 1892. Read 17 March 1892. Communicated by George Buchanan.

A version of this paper was published in volume 51 of the Proceedings of the Royal Society as 'On the causation of diphtheritic paralysis'.

Reference number

PP/19/5

Earliest possible date

1892

Physical description

Ink and graphite pencil on paper

Page extent

4 pages

Format

Manuscript