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Brunton and Pye describe some of the effects of Erythrophleum guinense on the body, including: that it diminishes oxidation, and thus prevents fresh vegetable tissues from communicating a blue colour to tincture of guaiac; that it does not hinder the development of the yeast-fungus nor the germination of seeds, and Penicillium grows freely in a solution of it; that a watery solution of the alcoholic extract prevents the development of bacteria, but one of the watery extract does not do so; that it does not destroy the life of bacteria or infusoria, and the motion of cilia is not arrested by it; that it arrests amoeboid movement in leucocyte; that it has no action on fresh muscular fibre, but muscular tissue, when kept in a solution of the alcoholic extract for some days, undergoes extensive fatty metamorphosis, but does not become putrid.

Annotations in pencil and ink throughout. Note on front reads 'Sections taken out before printing see Phil Trans 1877'.

Subject: Botany / Toxicology / Physiology

Read 15 June 1876.

Whilst the Royal Society declined to publish this paper in full, an abstract of the paper was published in volume 25 of the Proceedings of the Royal Society as 'Physiological action of the bark of erythrophleum guinense (casca, cassa, or sassy bark)'.

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Physical description
Ink and graphite pencil on paper
Page extent
109 pages

Creator name

Thomas Lauder Brunton

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Thomas Lauder Brunton, Unpublished paper, 'Physiological action of the bark of Erythrophleum guinense' by T [Thomas] Lauder Brunton and Walter Pye, 1876, AP/58/9, The Royal Society Archives, London,, accessed on 12 April 2024

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    Dates: 1768-1989

    The 'Archived Papers' collection is comprised of original manuscript scientific papers and letters submitted to the Royal Society which remained unpublished or were abstracted in the journal 'Proceedings of the Royal Society' published from 1830 onwards.

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