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The Royal Society: Science in the Making

Unpublished paper, 'Researches carried on at the pathological laboratory of St. Thomas's Hospital [London]. First series' by J L W [Johann Ludwig Wilhelm] Thudichum

Reference number: AP/49/8

Date: 1867

Description

Thudichum begins with a short historical retrospect on the literature of the subject under consideration, in which the researches of Berzelius, Scherer, Hein, Marchand, Heintz, Maly, and Städeler are mentioned. He then describes the mode of obtaining a red colouring matter from ox gallstones. These concretions have to be extracted with water, alcohol, ether, dilute hydrochloric acid, and ultimately, after repeated extraction with boiling alcohol and ether, with chloroform. This agent dissolves bilirubine or cholophaeine, and deposits it, on concentration and the addition of absolute alcohol, in an amorphous condition, or in a crystallised state. Thudichum describes the characteristics of these crystals.

Marked on front as 'Archives July 2/68'. Annotations in ink throughout. Includes one figure of crystallised cholophaeine.

Subject: Pathology

Received 14 November 1867. Read 12 December 1867. Communicated by John Simon.

Whilst the Royal Society declined to publish this paper in full, an abstract of the paper was published in volume 16 of the Proceedings of the Royal Society as 'Research conducted for the medical department of the privy council at the pathological laboratory of St. Thomas's Hospital. First series.—The chemical nature and composition, combinations, and metamorphoses of the colouring-matters of bile'.

Reference number
AP/49/8
Earliest possible date
1867
Physical description
Ink on paper
Page extent
45 pages
Format
Drawing
Manuscript

Creator name

J.L.W. Thudichum

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Citation

J.L.W. Thudichum, Unpublished paper, 'Researches carried on at the pathological laboratory of St. Thomas's Hospital [London]. First series' by J L W [Johann Ludwig Wilhelm] Thudichum, 1867, AP/49/8, The Royal Society Archives, London, https://makingscience.royalsociety.org/items/ap_49_8/unpublished-paper-researches-carried-on-at-the-pathological-laboratory-of-st-thomass-hospital-london-first-series-by-j-l-w-johann-ludwig-wilhelm-thudichum, accessed on 13 January 2025

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  • Archived Papers

    Dates: 1768-1989

    The 'Archived Papers' collection is comprised of original manuscript scientific papers and letters submitted to the Royal Society which remained unpublished or were abstracted in the journal 'Proceedings of the Royal Society' published from 1830 onwards.

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